General Information

Names: p-cresol, p-cresylic acid; 4-methylphenol
CAS: 106-44-5.

Formula: CH3C6H4OH.

Properties: Crystalline mass; phenol-like odor. Wt/gal 8.67 lb, d 1.039, bp 202C, mp 35.25C, flash p 187F (86C), autoign temp 1038F (558C). Soluble in alcohol, ether, chloroform, and hot water.

Derivation: (1) By fractional distillation of crude cresol; (2) from benzene by the cumene process (see phenol).

Method of purification: Crystallization.

Grade: Technical, 98%, 99.0% min purity or 34C min fp.

Hazard: TLV: 5 ppm.

 

Safety Information

General

Synonyms: 4-methylphenol, p-cresylic acid, 4-cresol, p-hydroxytoluene, 4-hydroxytoluene, p-methylphenol, para-cresol, p-tolyl alcohol, p-toluol
Molecular formula: CH3C6H4OH
CAS No: 106-44-5

Physical data

Appearance: crystals
Melting point: 34 C
Boiling point: 202 C
Vapour density: 3.7 (air = 1)
Vapour pressure: 0.1 mm Hg at 20 C
Density (g cm-3): 1.03
Flash point: 86 (closed cup)
Explosion limits:
Autoignition temperature:
Water solubility: moderate

Stability

Stable. Combustible. Incompatible with strong oxidizing agents. Light-sensitive.

Toxicology

Poison. May be fatal if swallowed. Readily absorbed through the skin. Harmful if swallowed or inhaled, and in contact with skin. Causes severe burns. Experimental neoplastigen. May cause serious eye damage. Severe skin and eye irritant. Typical TLV/TWA 5 ppm. Typical PEL 5 ppm.

Toxicity data

SCU-RAT LD50 500 mg kg-1
ORL-MUS LD50 344 mg kg-1
ORL-RBT LDLO 620 mg kg-1
ORL-RAT LD50 207 mg kg-1
SKN-RAT LD50 750 mg kg-1
IPR-MUS LD50 25 mg kg-1

Transport information

UN No 2076. Hazard class 6.1. Packing group II.

Personal protection

Safety glasses, gloves, adequate ventilation.